| 摘要: |
| 对应用于兽用疫苗研发的病毒载体，包括痘病毒载体、疱疹病毒载体、腺病毒载体、杆状病毒载体、副粘病毒载体、弹状病毒载体、甲病毒载体、冠状病毒载体、反转录病毒载体、黄病毒载体等DNA和RNA病毒载体的研究进展进行了综述,以期为我国基因工程活载体疫苗研发工作提供参考。 |
| 关键词: 病毒载体 兽用疫苗 基因工程活载体疫苗 |
| DOI： |
| 投稿时间：2012-08-07修订日期：2012-09-29 |
| 基金项目: |
|
| Research Progress of Viral-vector based Delivery Systems for Veterinary Vaccine |
|
| (China Institute of Veterinary Drug Control) |
| Abstract: |
| In order to provide reference for research of genetic engineering live vector vaccines in China, this paper reviews most of the viral-vector based antigen delivery systems (ADSs) recently developed for vaccine testing in veterinary species, including DNA and RNA viral vectors such as poxvirus vectors, herpesvirus vectors, adenovirus vectors, baculovirus vectors, paramyxovirus vectors, rhabdovirus vectors, alphavirus vectors, coronavirus vectors, retrovirus vectors, flavivirus vectors. |
| Key words: viral vectors veterinary vaccines genetic engineering live vector vaccines |
