| 摘要: |
| 采用高效液相色谱法对替米考星合成生产过程进行监控，对泰乐菌素原料A、B两种组分在合成替米考星反应过程中的变化进行了探讨，该项研究成功解决了替米考星合成过程中收率降低的问题。 |
| 关键词: 替米考星 泰乐菌素 高效液相色谱 合成 |
| DOI： |
| 投稿时间：2008-06-03修订日期：2008-07-31 |
| 基金项目: |
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| HPLC applied in monitoring the synthesis of tilmicosin |
| liuzhelin |
| (YanTai Luye animal health productc CO.LTD.) |
| Abstract: |
| High performance liquid chromatography (HPLC) method was used to monitor the production process of tilmicosin, and the problem of the change of tylosin A, B in the synthesis fo tilmicosin was discussed. This research has successfully solved the problem of low yield in the synthesis fo tilmicosin. |
| Key words: tilmicosin tylosin HPLC synthesis |
