| 摘要: |
| 多黏菌素是多肽类抗生素，对于多重耐药的革兰氏阴性菌具有良好的疗效。本文综述了多黏菌素的理化性质、抗菌活性、药动学、药效学、临床应用、残留等方面的特点和研究概况，以期为该药在兽医临床上的应用提供依据。 |
| 关键词: 多黏菌素 抗菌活性 药动学 药效学 临床应用 残留 |
| DOI： |
| 投稿时间：2008-11-03修订日期：2008-11-03 |
| 基金项目: |
|
| Polymyxin:A polypeptide antibacterial which has been applied to multi-drug-resistant gram-negative bacterial infections |
| gao yanling |
| (Henan Institute of Veterinary Drug Control) |
| Abstract: |
| Polymyxin is a polypeptide antibacterial which has good efficacy to multidrug-resistant Gram-negative bacteria.This review is mainly about spectrum of activity,pharmacokinetics,pharmacodynamics,toxicity,residues and clinical use of this drug. |
| Key words: :Polymyxin spectrum of activity pharmacokinetics pharmacodynamics clinical use residues. |
