| 摘要: |
| 建立癸氧喹酯预混剂的含量测定的方法。采用HPLC法，以十八烷基硅烷键合硅胶为填充剂，甲醇-水-冰醋酸（85：15：1）为流动相，检测波长为265nm。理论板数按癸氧喹酯峰计算不低于1500。经试验，癸氧喹酯在10～250μg / ml范围内峰面积与浓度呈良好的线性关系，回归方程Y=54.535X+10.231 г=1.000 (n=5) ，平均回收率为100.4%、100.3%、100.6%（n=3）。本方法具操作简便、快速、准确可靠等特点，适用于该药品生产的质量控制。 |
| 关键词: 高效液相色谱法 癸氧喹酯预混剂 含量测定 |
| DOI： |
| 投稿时间：2009-07-05修订日期：2009-10-09 |
| 基金项目: |
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| Determination of decoquinate Premix by HPLC |
| panqiwen |
| () |
| Abstract: |
| To establish a method for the determination of decoquinate Premix. HPLC method was adopted and a C18 column was used.The mobile was the mixture of methanol-water-glacial acetic acid(85:15:1).The UV detection wavelength was 265nm. The number of theoretical plates according to the decoquinate peak is not less than 1500.The standard curve was linear over the range of 10～250μg/ml with the correlation coefficient of r=1.000(n=5),The regression equation is Y=54.535X+10.231.The average recovery was 100.4%、100.3%、100.6%（n=3）. The methond appeared to be sample,quickly and accurate ,applicable to the product quality control. |
| Key words: HPLC ,decoquinate Premix ,content |
