| 摘要: |
| 泰妙菌素是一种截短侧耳素类动物专用抗生素，对支原体及某些革兰氏阳性菌感染具有良好的抗菌活性。本文综述了泰妙菌素的构效关系、抗菌机理及其活性、耐药及配伍性、药动学、残留、毒性研究、药效学研究及临床应用，以期为该药在兽医临床上的应用提供依据及认识。 |
| 关键词: 泰妙菌素 构效关系 抗菌机理及其活性 耐药及配伍性 药动学 残留 毒性研究 药效学研究及临床应用 |
| DOI： |
| 投稿时间：2009-07-08修订日期：2009-07-28 |
| 基金项目: |
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| Recent Advances in Research on Tiamulin |
| huanghexian |
| (Laboratory of Veterinary Pharmacology, College of Veterinary Medicine) |
| Abstract: |
| Tiamulin is a semisynthetic diterpene derivative of the antibiotic pleuromutilin and has a spectrum of activity against mycoplasmas and gram-positive bacteria organisms. The review is mainly about the structure-activity relationship spectrum of activity, pharmcokinetics, resistance and compatibility, detective method, pharmacodynamics,toxicity,residues,clinical use and preparation |
| Key words: Tiamulin the structure-activity relationship spectrum of activity resistance and compatibility pharmcokinetics pharmacodynamics toxicity residues clinical use |
