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中药制剂“球灭”颗粒剂成型工艺研究
唐顺龙
0
(西南大学动物科技学院)
摘要:
本研究考察“球灭”颗粒剂的最佳制粒处方组成,筛选出最佳组成为:干浸膏粉:可溶性淀粉=1:1.5,黏合剂为75%酒精;所制颗粒的吸湿率小、成型率高、溶化率高;结论试验结果可为“球灭”颗粒制剂处方组成的确定及生产环境的控制提供实验依据。
关键词:  “球灭”颗粒  成型工艺  临界相对湿度
DOI:
投稿时间:2010-06-06修订日期:2010-07-09
基金项目:
Study on Formulation Process of “Qiumie” Granule
tangshunlong
(Animal Science Technology College Southwest University)
Abstract:
To ascertain the best formulation process of “Qiumie” Granule,by determinating granulation, moisture conten,hygroscopicity and dissolubility of “Qiumie” Granule , we select the appropriate recipient.At last,the ration of powdered extract and excipient -is1 ∶1.5,meanwhile,the adhesive is 75% alcohol. The granules have low hygroscopicity and high granulation and high dissolubility. And it s critical relative humidity is 70 %.The experimental results provide the basis of the ascertainment of formulation process and the cont rol of product in viroment of “Qiumie” Granule.
Key words:  “QiumieGranule  formulation process  critical relative humidity

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