| 摘要: |
| 为了观察米尔贝肟片对犬弓蛔虫和钩虫驱虫效果，采用人工感染方式，对犬弓蛔虫和钩虫的动物模型进行疗效研究。结果表明，单次口服 0.5 mg?kg-1 米尔贝肟片对犬弓蛔虫和犬钩虫的虫卵减少率、驱虫有效率和治愈率均可达到100%。说明米尔贝肟片在治疗犬弓蛔虫和钩虫时具有剂量小、疗效高、作用快、副反应轻等特点，在临床治疗方面有十分广阔的应用前景。 |
| 关键词: 米尔贝肟（片） 犬弓蛔虫 犬钩虫 疗效观察 |
| DOI： |
| 投稿时间：2010-12-12修订日期：2011-03-11 |
| 基金项目:“十一五”国家科技支撑计划项目(2006BAD31B02) |
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| THERAPEUTIC OBSERVATION OF MILBEMYCIN OXIME TABLET ON TOXOCARA CANIS AND ANCYLOSTOMA CANINUM |
| yuxiaolei |
| (dongbeinongyedaxueyaolijiaoyanshi) |
| Abstract: |
| To observe the anthelmintic efficay of Milbemycin oxime on Toxocara canis and Ancylosloma caninum , animal models of Toxocara canis and A. caninum in dogs were administrated milbemycin oxime at a single oral dose of 0.5 mg?kg-1 . The result showed that, for Toxocara canis and A. caninum, the egg reduction rate, anthelmintic rate and curative rate all were 100%. Therefore Milbemycin oxime is a hopeful anthelmintic drug with small dose, high efficacy, quick action and little side effect. |
| Key words: Milbemycin oxime tablet Toxocara canis Ancylostoma caninum therapeutic observation |
