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氟苯尼考及其制剂的拉曼光谱检测研究
邵德佳,戚雪勇
0
(江苏省兽药饲料质量检验所;江苏大学药学院)
摘要:
用显微拉曼光谱仪,研究了氟苯尼考及其同类药物甲砜霉素、氯霉素的拉曼光谱以及氟苯尼考制剂的拉曼光谱,并对其拉曼光谱进行了简单分析。结果表明该方法使用简单,分析速度快,能准确区别氟苯尼考、甲砜霉素、氯霉素三种药物结构上的差别,能初步判断制剂是否为可疑假兽药,是一种快速、识别率高的定性方法。
关键词:  拉曼光谱  氟苯尼考  甲砜霉素  氯霉素  氟苯尼考制剂
DOI:
投稿时间:2011-05-25修订日期:2011-06-25
基金项目:
A Study on Raman Spectroscopy for Detecting Florfenicol and Its Preparation
SHAO De-jia
(Jiangsu Provincial Institute for Veterinary Drug and Feed Quality Control)
Abstract:
A new method was proposed for detecting the Florfenicol and other similar drug like thiamphenicol and chloramphenicol and Florfenicol’s preparation quickly with Raman spectroscopy. Based on the theoretical analysis of these Raman spectrums, experimental results showed that this approach could be used to distinguish different structure of three drugs accurately and make the preliminary judgment where the preparations was the false and inferior veterinary drug. Raman spectrums was a simple, fast testing technology with a high recognition rate.
Key words:  raman spectroscopy  florfenicol  thiamphenicol  chloramphenicol  florfenicol’s preparation

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