| 摘要: |
| 维生素B12生产菌2009-106株经重离子50 Gy诱变处理得106-8株，其摇瓶单位较出发菌株2009-106提高了31％，对其发酵培养基优化后，应用于120吨发酵罐生产，明显提高产量。 |
| 关键词: 维生素B12 重离子注入诱变，选育高产菌株 |
| DOI： |
| 投稿时间：2011-08-17修订日期：2011-10-30 |
| 基金项目: |
|
| Filter paper tubes preserved in Tylosin Production |
| niuchun |
| (Ningxia kingvit pharmaceutical Co., LTD) |
| Abstract: |
| Vitamin B12 producing strain 2009-106 was mutated by 50 Gy heavy ion into strain 106-8. Compared with the original strain2009-106，the relative flask potency of strain106-8 increased31%. After optimization of fermentation medium, it was used in120 tons fermentation can, and increased production obviously. |
| Key words: vitamin B12 heavy ion implantation, breeding high-yield strains. |
