| 摘要: |
| 为制备稳定的液体石蜡乳剂，选用多元醇作为辅助乳化剂，采用单因素试验法筛选了乳剂油相、乳化剂种类及油水比例，初步确定了乳剂配方；采用正交试验设计对初定配方和生产工艺进行优化，最终筛选出乳剂的理想配方和生产工艺。乳剂的配方为油相60 mL，乳化剂吐温-80 1.5 mL，辅助乳化剂丙二醇1.5 mL，水38.5 mL，生产工艺为室温条件下以800 r/min搅拌速度乳化7 min。稳定性试验表明，研制的液体石蜡乳剂稳定性良好。 |
| 关键词: 液体石蜡乳剂 多元醇 稳定性 |
| DOI： |
| 投稿时间：2013-06-18修订日期：2013-11-20 |
| 基金项目: |
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| Preparation and Stability Evaluation of Liquid Paraffin-emulsion |
|
| (Heilongjiang Institute of Veterinary Medicine Science,Qiqihaer) |
| Abstract: |
| The objective of this experiment is to preparation W/O emulsion by D-phase emulsification and evaluation it′s stability. Screening of the oil phase, the emulsifie species , the amount of emulsifie and the oil-water ratio by the univariate analysis, The basic formula of W/O emulsion were determined. The optimum formulation and preparation technology of W/O emulsion were determined by means of orthogonal test, finally. The formulation of O/W emulsion was composed by oil phase 60mL,span 80 1.5mL, propanediol 1.5mL, water 38.5mL. The optimum preparation technology was determined that emulsifying time 5 min, stirring speed 800r/min at room temperature. The experimental results indicated that the W/O emulsion has better stability. |
| Key words: Liquid Paraffin-emulsion polyalcohol stability |
