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硫酸头孢喹肟注射液对仔猪传染性胸膜肺炎的临床疗效试验
周德刚,郭亚楠
0
(国家兽用药品工程技术研究中心)
摘要:
将硫酸头孢喹肟注射液分为高、中、低(4、2、1mg/kg体重)3个剂量组分别肌肉注射治疗仔猪传染性胸膜肺炎,同时设头孢噻呋冻干粉对照组,按3 mg/kg体重给药,一日一次,连用3天。结果表明,硫酸头孢喹肟注射液3个剂量组和阳性对照组(头孢噻呋冻干粉对照组)对仔猪传染性胸膜肺炎均有明显的治疗效果,有效率及相对增重率显著高于阴性对照组(P<0.01);硫酸头孢喹肟注射液高、中剂量组的有效率及相对增重率显著高于硫酸头孢喹肟注射液低剂量组和阳性对照组((P<0.01)。人工感染治疗试验结果表明硫酸头孢喹肟注射液按每1kg体重2mg肌注,一日一次,连用3天,对仔猪传染性胸膜肺炎有良好的治疗效果。
关键词:  硫酸头孢喹肟注射液  猪传染性胸膜肺炎  临床疗效
DOI:
投稿时间:2013-06-23修订日期:2013-09-01
基金项目:“十一五”国家科技支撑计划(2006BAD31B06)
Observation of the Clinical Effect of Cefquinome Sulfate Injection on Artificial Infection of Piglet Contagious Pleuropneumonia
(National Research Center for Veterinary Medicine,Luoyang,Henan)
Abstract:
The experiment was conducted to use three dosage levels of cefquinome sulfate injection (4, 2, 1 mg/kg) and ceftiofur freeze-dried powder (3mg/kg) once a day for 3 days to cure piglet pleuropneumonia by intramuscular injection.The results showed that both cefquinome sulfate injection of three inclusion levels and ceftiofur freeze-dried powder as medicine control group have significantly therapeutic efficacy on piglet contagiows pleuropneumonia and the effective rate and weightgainrate(WGR) was distinguished higher than the negative control group(P< 0.01). Especially, the high and the medium level of cefquinome sulfate injection had higher effective rate and WGR than the low levels of cefquinome sulfate injection and positive control group (ceftiofur freeze-dried powder) (P<0.01).Artificial infection experiment indicated that the level of cefquinome sulfate injection (2mg/kg, once a day for 3 days) had better effect as injection on curing Actinobacillus pleuropneumoniae.
Key words:  Cefquinome sulfate injection  Porcine infectious pleuropneumonia  Clinical effect

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