| 摘要: |
| 为了优选芩黄颗粒的最佳提取工艺,方中麻黄水提工艺以浸膏收率和麻黄碱含量为指标,黄芩、甘草、山豆根、桔梗和板蓝根群药水煎煮工艺以浸膏收率、黄芩苷及甘草酸含量为指标,采用正交试验法对芩黄颗粒进行提取条件的筛选。结果麻黄最佳提取工艺为加8倍量水真空动态(≤70℃)提取6小时；黄芩、甘草、山豆根、桔梗和板蓝根群药最佳提取工艺为加10倍量水真空动态(≤70℃)提取4小时。优选出的最佳提取工艺合理、稳定,适合工业化大生产。 |
| 关键词: 芩黄颗粒 提取工艺 正交试验 |
| DOI： |
| 投稿时间：2013-06-23修订日期：2013-08-16 |
| 基金项目: |
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| Extraction Process of Qinhuang Granules |
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| (National Research Center for Veterinary Medicine,Luoyang,Henan,471003) |
| Abstract: |
| To study the best extraction process of Qinhuang granules, the obtaining rate of extraction and the ephedrine content were taken as indexes for the water extraction process of Ephedrae Herb, and the obtaining rate of extraction, the baicalin content and the glycyrrhizic acid content as indexes for the water decoctionextraction process of Scutellariae Radix, glycyrrhizae radix, radix sophorae tonkinensis, platycodon grandiflorum and Indigowoad Root. The extraction process of Qinhuang granules was optimized by orthogonal design. The optimal conditions for the water extraction of Ephedrae Herba was 8-fold amount of water, reflux 6 hours(≤70℃). The optimal conditions of Scutellariae Radix, glycyrrhizae radix, radix sophorae tonkinensis, platycodon grandiflorum and Indigowoad Root was 10-fold amount of water, reflux 4 hours (70℃). The extracting method is reasonable, stable, and suitable for industrialized production. |
| Key words: Qinhuang granules Extraction process Orthogonal design |
