| 摘要: |
| 为研究夏枯草注射液的抗炎及抗菌作用，用二甲苯、蛋清分别造成小鼠和大鼠炎症模型来考察夏枯草注射液的抗炎作用，通过体外、体内抑菌试验来评价其抗菌作用。结果显示，夏枯草注射液能显著抑制二甲苯所致的小鼠耳肿胀和对蛋清致大鼠足跖肿胀，体外抗菌实验表明夏枯草注射液对痢疾杆菌、大肠杆菌、肺炎双球菌、溶血性链球菌有较好的抑菌作用，夏枯草注射液对腹腔注射肺炎双球菌ATCC 27853引起小鼠死亡的保护作用。因此，夏枯草注射液具有抗炎、抗菌作用，该试验可为夏枯草注射液的临床应用提供依据。 |
| 关键词: 夏枯草注射液 抗炎 抗菌 |
| DOI： |
| 投稿时间：2014-09-03修订日期：2014-10-06 |
| 基金项目: |
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| The anti-inflammation and antibacterial effect of Seaelfhl injection |
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| (Shanxi Institute of Veterinary Drug Control;Jiangxi New Century Minxing Animal Health Products Co,Ltd Jiangxi Nanchang) |
| Abstract: |
| In order to study the anti-inflammatory and antibacterial effect of Selfheal injection, a inflammatory model for mouse and rat was constructed by using dimethylbenzene and egg white, through the antibacterial?test in vivo?and?in vitro to evaluate the antibacterial action. The result shows that Seaelfhl injection can inhibit the mouse ear edema induced by dimethylbenzene, and inhibit the rat?foot swelling?induced?by egg white. Antimicrobial test in vitro shows that Seaelfhl injection has the function of inhibiting the growth of shigella dysenteriae, Escherichia coli, diplococcus pneumoniae and hemolytic streptococcus. Seaelfhl injection can also protect the mouse from death induced by diplococcus pneumoniae ATCC 27853. The result prove that Seaelfhl injection has the effect of anti-inflammatory and antibacterial, the test can provide basis for clinical practice of Seaelfhl injection. |
| Key words: Seaelfhl injection anti-inflammatory antibacterial |
