| 摘要: |
| 为改善3-甲基-2-[3-（2-呋喃基）丙烯甲酰]-喹喔啉- 1,4-二氮氧化物的制备工艺，寻找一种与喹烯酮结构相似，但药效更好、毒性更低的喹喔啉类兽药，对环氧化反应条件，乙酰甲喹制备工艺，目标产物制备条件进行了研究。优化了催化剂用量，缩短了反应时间，提高了目标产物的产率。合成的产物经理化性质和光谱分析证明系为所合成的目标产物。 |
| 关键词: 兽药 合成 喹喔啉 光谱分析 |
| DOI： |
| 投稿时间：2015-03-19修订日期：2015-05-22 |
| 基金项目: |
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| Study on the synthesis of 3- methyl-2-[3-(2-furyl)propylene formyl-quinoxaline-1,4-two oxides of nitrogen |
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| (China Agriculture University(yantai)) |
| Abstract: |
| In order to improve the preparation process of study on the synthesis of 3- methyl-2-[3-(2-furyl)propylene formyl-quinoxaline-1,4-two oxides of nitrogen, and seek a similar structure with Quinocetone,but have better efficacy, less toxicity quinoxaline veterinary drugs,This studies the reaction conditions of epoxidation ,the process of Mequindox preparation and the preparation conditions of the target . It optimizes the dosage of the catalyst, shortens the reaction time and improves the yield of target product. The products synthesized by physical and chemical properties and spectral analysis ,it proves the synthesized product for the target 。 |
| Key words: Veterinary drugs Synthesis process QuinoxalineScompounds Spectral analysis |
