| 摘要: |
| 建立了那西肽预混剂组分测定的高效液相检查法。采用十八烷基键合硅胶为填充剂，以0.025%磷酸水溶液-乙腈（50:50）为流动相，检测波长为241 nm，以该色谱条件对来自7个厂家的14批不同规格的那西肽预混剂进行了测定。综合结果给出的组分的建议限度为那西肽组分A的峰面积不得少于那西肽组分A与组分B峰面积之和的88.0%。该方法具有专属性强、耐用性好、操作简便等优点。 |
| 关键词: 那西肽预混剂 组分 高效液相色谱法 |
| DOI： |
| 投稿时间：2015-08-19修订日期：2015-09-28 |
| 基金项目: |
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| The Establishment of The HPLC Method to Determine Component in Nosiheptide Premix |
|
| (China Institute of Veterinary Drug Control) |
| Abstract: |
| The HPLC method of component determination for Nosiheptide premix was established. The operation conditions were performed on C18 column with a mobile phase of 0.025% phosphoric acid solution-acetonitrile (50:50). The detection wavelength was 241 nm. According to this method, the component of 14 batches of Nosiheptide premix from 7 manufacturers was determined. Based on the results, a proposed limitation of the component was given: the peak area of Nosiheptide component A can not less than 88.0% of the total peak area of component A and B.This method has special property, good durability and simple operation. |
| Key words: Nosiheptide premix component HPLC method |
