| 摘要: |
| 氟苯尼考广泛应用于兽医临床防治猪、牛等动物的细菌感染性疾病。近年来该药在药效学以及药动学等方面已有了广泛研究，从氟苯尼考的理化性质、抗菌机理、耐药性、药效学、药动学、水溶性、联合用药以及药剂学等方面进行综述，以期为扩大该药在兽医临床上的应用范围以及新制剂的研制提供参考。 |
| 关键词: 氟苯尼考 研究进展 |
| DOI： |
| 投稿时间：2016-08-25修订日期：2016-09-02 |
| 基金项目:国家自然科学基金"氟苯尼考对猪链球菌的药动学-药效学同步模型研究"(31660729)；塔里木大学校长基金-青年创新资金项目"氟苯尼考纳米混悬剂的制备"(TDZKQN201603) |
|
| Advance in the Research of Florfenicol |
|
| (Key Laboratory of Tarim Animal Husbandry Science and Technology of Xinjiang Production Construction Corps,Alar) |
| Abstract: |
| Florfenicol is a new broad-spectrum antimicrobial and belonged to chloramphenicol class with called “star of anti-microbial”, which was widely used in veterinary clinical for prophylaxis and treatment of bacterial infectious diseases in swine, bovine and so on. It had been widely studied on pharmacodynamics (PD), pharmacokinetics (PK) and so on in recent years. And this paper summed up the physical and chemical properties, antibacterial mechanism, drug resistance, PD, PK, water-soluble, combination drug therapy and pharmaceutics of florfenicol to expand its applied range and provide some references for new preparation. |
| Key words: florfenicol research review |
