| 摘要: |
| 为确定乌梅颗粒的最佳制备工艺，采用正交试验的方法，对乌梅颗粒的提取工艺进行研究、通过颗粒的成型率、流动性和有效成分的检测等条件对制备成型工艺进行摸索，结果表明，称取处方量乌梅、柿饼和诃子经提取浓缩后得浸膏相对密度为1.30-1.35，黄连和姜黄采用混合粉碎，以3000r/min转速混合30min。颗粒剂辅料选用蔗糖和糊精，其浸膏+药粉∶蔗糖∶糊精最佳比例为1:0.3:1。乌梅颗粒的制备工艺简单，质量可控，可作为最佳制备工艺。 |
| 关键词: 乌梅颗粒 工艺研究 正交试验 |
| DOI： |
| 投稿时间：2018-09-16修订日期：2019-01-13 |
| 基金项目: |
|
| Study on preparation technology of wumei granules |
| 尚静雪 |
| (Inner Mongolia huatian pharmaceutical co.,LTD.,Inner Mongolia chifeng 024070.) |
| Abstract: |
| To determine the best preparation technology of ebony particles, using the method of orthogonal test, the extraction process of ebony particles are studied, through particles forming rate, liquidity and effective components of detection conditions on the preparation for molding process, the results showed that the said take prescriptions of plum, dried persimmon and myrobalan after extraction enrichment to extract the relative density of 1.30-1.35, rhizoma coptidis and turmeric with mixed shattered, 30 min to 3000 r/min speed mixed.The granule excipients were sucrose and dextrin, and the best proportion of the extract + powder: sucrose: dextrin was 1:0.3:1. The preparation process of wumei granules is simple and controllable. |
| Key words: Wumei granules Technical study Orthogonal test |
