| 摘要: |
| 基于抗寄生虫药物应用面临的问题以及在预防和治疗寄生虫病中的重要作用，固体脂 质纳米（ＳＬＮｓ）因其独特的优势成为当前研究的热点。 从 ＳＬＮｓ 可以提高抗寄生虫药物的口服吸收、 增强胞内感染治疗疗效、提高药物安全性和渗透性能以及靶向性传递等四个方面阐述了目前 ＳＬＮｓ 在抗寄生虫药物传递中的研究现状，为后续进一步研究提供参考。 |
| 关键词: 固体脂质纳米 抗寄生虫药物 研究现状 |
| DOI： |
| 投稿时间：2019-10-05修订日期：2020-01-07 |
| 基金项目:国家重点研发计划专项“畜禽重要病原耐药性检测与控制技术研究”（2016YFD0501309） |
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| Research Progress of Application of Solid Lipid Nanoparticles (SLNs) in Antiparasitic Drugs |
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| (Huangzhong Agricultural University) |
| Abstract: |
| Based on the current problems faced by antiparasitic drugs and the important role in the preventive and treatment of parasitic diseases, soild lipid nanoparticles(SLNs)has become a research hotspot because of its unique advantages.The current research status of SLNs in anti-parasitic drugs was described from four aspects, including improving oral absorption of antiparasitic drugs, enhancing therapeutic effect of intracellular infection, improving drug safety, osmotic performance and targeted delivery of SLNs, providing reference for further studies. |
| Key words: solid lipid nanoparticles (SLNs) antiparasitic drugs oral absorption intracellular delivery research progress |
