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我国猪源和鸡源大肠杆菌抗生素耐药性相关基因研究进展
周炜,周芷锦,沈红霞,倪柏锋,王彬,陈凯,穆琳,陈勇,张恩宝,曲道峰,赵灵燕
0
(浙江省动物疫病预防控制中心)
摘要:
大肠杆菌,作为一种条件致病菌和重要的耐药性指示菌,国内外已有大量猪源、鸡源大肠杆菌耐药性相关基因的研究报道。受动物种属、地域等来源性差异,以及耐药机制、亚型等因素的影响,研究中涉及很多种不同的耐药性相关基因,且检出率也不尽相同。论文主要根据耐受抗菌药物种类,对这些基因作用机理及分布情况等方面进行综述,以期为研究大肠杆菌耐药性产生机制提供依据及参考。
关键词:  猪源大肠杆菌  鸡源大肠杆菌  抗生素耐药性  耐药基因
DOI:
投稿时间:2020-10-19修订日期:2021-07-01
基金项目:浙江省重点科技研发项目
Progress on the antibiotics resistance related genes of Escherichia coli from swine and chicken in China
(zhejiang provincial center for animal disease prevention and control,Hangzhou,Zhejiang,311119;China)
Abstract:
As an important indicator and pathogen, a large scale of antibiotics resistance related genes of Escherichia coli (E. coli) from animals have been reported, both at home and abroad. Due to the differences of animal species and regions, as well as antibiotics resistance mechanism, subtypes and other factors, many kinds of antibiotics resistance related genes were involved, and their detection rates were quit differently. In this paper, the mechanism of actions and distributions of these genes were reviewed, according to the types of antibiotic, in order to provide reference for the study of the mechanism of drug resistance in E.coli.
Key words:  swine-drived E.coli  chicken-drived E.coli  antibiotics resistance  antibiotic resistance genes

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