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动物源性中药材兽药残留检测技术研究进展
许晓辉,李剑勇,朱仁愿,潘秀丽,李晨曦,王小乔
0
(兰州市食品药品检验检测研究院)
摘要:
[]动物源性中药材兽药残留问题是影响动物源性中药材质量安全的主要风险因子之一,服用含有兽药残留的动物源性中药材,不但会降低药效,而且会使人体产生过敏反应和抗生素耐药性等,甚至损害人体器官。加强动物源性中药材兽药残留检测,从源头进行质量控制,使动物源性中药材兽药残留早发现、早预警、早处置,使监管前移,做好风险预测与研判,是当前动物源性中药材质量控制急需解决的问题。本文从动物源性中药材兽药残留检测现状、检测方法研究思路和基质效应评价等方面探讨了兽药残留高通量检测技术的研究与应用,以期为加强动物源性中药材兽药残留高通量检测研究与质量安全控制提供参考。
关键词:  []动物源性中药材  兽药残留  检测技术
DOI:
投稿时间:2020-10-27修订日期:2021-04-26
基金项目:甘肃省药品监督管理局科学技术类项目(2020GSMPA032)
A Brief Analysis of Detecting Technology of Veterinary Drug Residue in Animal-Derived Chinese Medicinal Materials
(Lanzhou Institute for Food and Drug Control,Gansu Lanzhou)
Abstract:
The problem of veterinary drug residues in animal-derived Chinese medicinal materials is one of the main risk factors, which affecting the quality and safety of animal-derived Chinese medicinal materials. Taking Chinese medicinal materials that contain veterinary drug residues will not only reduce the effect of treatment, but also cause allergic reaction and antibiotic resistance in human body, and even damage human organs. Strengthen the detection of veterinary drug residues in animal-derived Chinese medicinal materials, control quality from the source, make early detection, make early warning, make early disposal of veterinary drug residues in animal-derived Chinese medicinal materials, make supervision move forward, and do a good job in risk prediction and research and judgment, which are urgent problems to be solved in the current quality control of animal-derived Chinese medicinal materials. This paper discusses the research and application of high-throughput detection of multi-veterinary drug residue in animal-derived Chinese medicinal materials from three aspects:the current situation of multi-veterinary drug residue detection, the research ideas of detecting method and evaluation of matrix effect, in order to provide reference for strengthening the high-throughput detection and quality safety control of veterinary drug residue in animal-derived Chinese medicinal materials.
Key words:  Chinese medicinal materials of animal origin  veterinary drug residue  detecting technology

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