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| 猪圆环病毒2型疫苗及其效力评价方法比较研究 |
| 徐嫄,彭国瑞,徐小艾,吴睿智,赵启祖,朱元源,李翠,王团结,邹兴启,李琰,刘业兵 |
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| (中国兽医药品监察所) |
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| 摘要: |
| 为探索对不同猪圆环病毒2型（Porcine Circovirus Type 2, PCV2）疫苗产品进行统一质量评价的可行性，本文对国内该类疫苗产品及其现有效力评价方法进行了归纳和比较研究。结果发现，目前圆环病毒2型疫苗类产品种类有25个，且疫苗毒株数量多达10余个，效力检验方法包括传统的免疫攻毒法、血清学方法和多种不同的替代方法，但尚没有统一的效力评价体系。本研究为进一步完善PCV2疫苗效力评价方法、统一评价疫苗效力、提高产品质量，提供参考依据。 |
| 关键词: 猪圆环病毒2型 疫苗 效力评价方法 |
| DOI： |
| 投稿时间：2023-09-14修订日期：2023-11-13 |
| 基金项目:兽药行业公益性重点专项(GY202102) |
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| Comparative Study on the Porcine Circovirus Type 2 Vaccine and Its Efficacy Evaluation Method |
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| (China Institute of Veterinary Drug Control) |
| Abstract: |
| In order to explore the feasibility of conducting a unified quality evaluation of different Porcine Circovirus Type 2 (PCV2) vaccine products, this paper has conducted a comparative study on the PCV2 vaccine products and their existing efficacy evaluation methods in China. The results showed that there are currently 25 PCV2 vaccine products, with more than 10 vaccine strains. The efficacy test methods include the traditional vaccinate-challenge method, serology test, and various alternative methods. However, there is no unified efficacy evaluation system. This paper provides a reference for further improving PCV2 vaccines efficacy evaluation methods, unifying the evaluation of vaccines efficacy and improving the quality of vaccine products. |
| Key words: Porcine circovirus type 2 Vaccines Efficacy evaluation method |
