| 摘要: |
| [摘要] 概述产蛋鸡（蛋鸡、种鸡及后备母鸡）用药物弃蛋期的制定考虑因素。根据欧盟EMA发布的欧盟最大残留限量制定指南、残留消除指南以及FDA发布的食品动物用新兽药对人类食品安全性评价的一般原则，结合已经批准的部分零日弃蛋期药物，浅析弃蛋期制定的方法和一般考虑。制定产蛋鸡用药物弃蛋期需要考虑最大残留限量、ADI合理分配、鸡蛋中药物的残留消除，其中最重要的因素是ADI合理分配。 |
| 关键词: 产蛋鸡用药物； 最大残留限量 ADI合理分配；零日弃蛋期 |
| DOI： |
| 投稿时间：2020-09-11修订日期：2020-11-18 |
| 基金项目: |
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| Analysis on Establishment of the Zero - Egg Withdrawal Period for Veterinary Medicine Used in Laying Hens |
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| (Cnina Institute of Veterinary Drug Control) |
| Abstract: |
| Abstract: To summarize the factors affecting the egg withdrawal period establishment of veterinary medicine used in laying hens (layers, breeders and pullets). The methodological principles for the risk management recommendations referred to in Article 7 of Regulation (EC) No 470/2009 and residue depletion studies which released by EU, and General Principles for Evaluating the Human Food Safety of New Animal Drugs Used in Food-Producing Animals which released by FDA are included. The methods and factors for egg withdrawal period establishment are reviewed in combination with some approved veterinary medicine with zero - egg withdrawal period. To establish egg withdrawal period should be focused on a set of studies such as maximum residue limits (MRL) , ADI rational partition, and egg residue depletion study and so on. ADI rational partition is the key factor. |
| Key words: veterinary medicine for laying hens maximum residue limits zero-egg withdrawal period ADI rational partition |
